David M. Waisman
David Waisman is a Professor in the Department of Pathology at Dalhousie University and formerly held a Canada Research Chair in Cancer Research. Renowned for his pioneering work on the pathobiology of cancer, his research focuses on the mechanisms of tumor growth and metastasis, particularly in breast, pancreatic, and lung cancers. His most significant contributions include discovering how the protein S100A10 regulates plasmin production and drives tumor growth, invasion, and metastasis. This discovery has significantly advanced our understanding of cancer cell invasion and opened new possibilities for targeted therapies to inhibit cancer spread. His work also led to the discovery of the protein calreticulin (CRT). It redefined CRT as a key regulator of plasmin-mediated proteolysis in cancer. This finding has revolutionized our understanding of cancer progression. Dr. Waisman has been a faculty member at Dalhousie since 2006.